服務(wù)熱線
400-1016-218
聯(lián)系方式
- 手機：400-1016-218
- Q Q：355185756
- 郵箱：355185756@qq.com
- 地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學(xué)科技園A401室
Anti -MEKK3 Rabbit pAb
價格：
在線咨詢
貨號：
KT012260
產(chǎn)品規(guī)格：
100ul
Applications：
WB
Species：
H/M/R
購買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項
Product Information
|
Description |
MEKK3 rabbit polyclonal antibody |
|
Protein full name |
Mitogen-activated protein kinase kinase kinase 3 |
|
Synonyms |
MAPK/ERK kinase kinase 3, MEK kinase 3, MEKK 3, Map3k3, Mekk3 |
|
Immunogen |
Recombinant protein corresponding to Mouse MEKK3 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
71 kDa |
|
Observed MW. |
78 kDa |
|
Uniprot ID |
Q99759, Q61084, B5DF98 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 800-1: 1000 |
liver, lung |
Background
The mitogen-activated protein/ERK kinase kinase 3 (MEKK3) is a member of a family of MEKK/Ste11 serine/threonine protein kinases. One function of MEKK3 is to serve as an upstream regulatory kinase in the mitogen activated protein kinase cascade, however, it also plays a critical role in other signaling pathways. MEKK3 regulates several important functions including cell survival and proliferation. It is ubiquitously expressed in multiple tissues and has been found in complexes with scaffold proteins and other kinases.Cerebral cavernous malformations (CCMs) complex regulation of MEKK3 is essential during vertebrate heart development. MEKK3 signalling and KLF2/4 may be targeted to develop new CCM therapeutics.
Images
|
|
Western blot analysis of mekk3 at dilution of 1: 800 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
凡合肥萬物生物科技有限公司銷售的產(chǎn)品均有嚴格的質(zhì)量保證。如發(fā)現(xiàn)產(chǎn)品存在包裝規(guī)格疑問，請于收貨之日起七日內(nèi)向我公司總部或當?shù)剞k事處提出，并請保證該產(chǎn)品，以備本公司進行核對檢驗。如果發(fā)現(xiàn)有質(zhì)量問題，請于收貨后一月內(nèi)保留產(chǎn)品50%以上的量，以便本公司回收產(chǎn)品進行質(zhì)檢，確認產(chǎn)品質(zhì)量。如逾期，則視為已經(jīng)對本公司產(chǎn)品進行驗收。 聲明：如發(fā)生產(chǎn)品索賠事宜，本公司僅在產(chǎn)品價格范圍內(nèi)酌情賠償，恕不接受超出產(chǎn)品價格范圍之賠償?？蛻粼谑褂眠^程中有任何技術(shù)問題可以撥打技術(shù)售后服務(wù)電話我們隨時給予解答。
合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學(xué)科技園A401室