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Anti -p38 Rabbit pAb

價(jià)格: 在線咨詢
貨號:
KT012255
產(chǎn)品規(guī)格:
100ul
Applications:
IHC/IF
Species:
H/M/R
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information



Description

P38  rabbit polyclonal

Protein full name Mitogen-activated protein kinase 14
Synonyms

MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2,PRKM14,PRKM15, RK, SAPK2A,p38,p38ALPHA, mitogen-activated protein kinase 14

Immunogen KLH conjugated Synthetic peptide corresponding to Mouse P38
Isotype IgG
Purity Affinity purification
Subcellular location Cytoplasm, Nucleus
Uniprot ID Q16539,P47811,P70618




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 1000-1: 2000

kidney, lung, lung cancer, testis




Background


MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such asproliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress-related transcription and cell cycle regulation, as well as in genotoxic stress response.




Images



Picture 1.png

Immunohistochemistry of paraffin embedded human lung cancer using P38 

 at dilution of 1:1000 (400x lens)

Picture 2.png

Immunohistochemistry of paraffin embedded mouse kidney using P38  at dilution of 1:1000 (400x lens)


Picture 3.png


Immunohistochemistry of paraffin embedded mouse lung using P38at dilution of 1:1000 (400x lens)

Picture 4.png

Immunohistochemistry of paraffin embedded mouse testis using P38  at dilution of 1:1000 (400x lens)

Picture 5.png

Immunohistochemistry of paraffin embedded rat kidney using P38 at dilution of 1:1000 (400x lens)


Picture 6.png

Immunohistochemistry of paraffin embedded rat lung using P38 at dilution of 1:1000 (400x lens)

Picture 7.png

Immunohistochemistry of paraffin embedded rat testis using P38at dilution of 1:1000 (400x lens)




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100μg/ml BSA and 50% glycerol.




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