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Product Information
Description |
MTA1 rabbit polyclonal antibody |
Protein full name |
Metastasis-associated protein MTA1 |
Synonyms |
MTA1, Metastasis-associated 1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse MTA1 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
81 kDa |
Observed MW. |
81 kDa |
Uniprot ID |
Q13330 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human |
1: 500-1: 1000 |
MCF7, 293T, NIH/3T3 |
Background
Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator. Regulates p53-dependent and -independent DNA repair processes following genotoxic stress. Plays an important role in tumorigenesis, tumor invasion . Plays a role in the regulation of the circadian clock . May be involved in the regulation of gene expression by covalent modification of histone proteins. Isoform Long is a corepressor of estrogen receptor (ER). Isoform Short binds to ER and sequesters it in the cytoplasm and enhances non-genomic responses of ER. With TFCP2L1, promotes establishment and maintenance of pluripotency in embryonic stem cells (ESCs) and inhibits endoderm differentiation (By similarity).
Images
|
Western blot analysis of MTA1 (GB111042) at dilution of 1: 500 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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