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Product Information
Description |
Rad21 rabbit polyclonal antibody |
Protein full name |
Double-strand-break repair protein rad21 homolog |
Synonyms |
hHR21, Nuclear matrix protein 1, NXP-1, SCC1 homolog, 64-kDa carboxy-terminal product, Rad21, HR21, KIAA0078, NXP1, SCC1 |
Immunogen |
Recombinant protein corresponding to Mouse Rad21 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
72 kDa |
Observed MW. |
75 kDa/130 kDa |
Uniprot ID |
O60216 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Human |
1: 500-1: 1000 |
HeLa, THP-1, K562 |
Background
RAD21, also named as Nuclear matrix protein 1, which belongs to the rad21 family. The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
Images
|
Western blot analysis of RAD21 (GB111435) at dilution of 1: 500 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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