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Product Information
Description |
Exonuclease 1 rabbit polyclonal |
Protein full name |
Exonuclease 1 |
Synonyms |
mExo1, Exonuclease 1, Exo1, HEX1, hExoI, rad2 nuclease family member, Homolog of S, cerevisiae exonuclease 1 |
Immunogen |
Recombinant protein corresponding to Mouse Exonuclease 1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Nucleus |
Uniprot ID |
Q9QZ11 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Rat |
1: 900-1: 1800 |
testis, brain |
IF |
Rat |
1: 900-1: 1800 |
brain |
Background
EXO1 also named as HEX1, is a protein with 5' to 3' exonuclease activity as well as an RNase H activity, which belongs to the XPG/RAD2 endonuclease family.EXO1 as 5'->3' double-stranded DNA exonuclease, which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. EXO1 functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch.
Images
|
Immunohistochemistry analysis of paraffin-embedded rat testis using Exo1 (GB111399) at dilution of 1: 900 |
|
Immunohistochemistry analysis of paraffin-embedded rat brain using Exo1 (GB111399) at dilution of 1: 900 |
|
Immunofluorescent analysis of paraformaldehyde-fixed rat brain using Exo1 (GB111399) at dilution of 1: 900 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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