Anti -BRCA2 Rabbit pAb

價格：在線咨詢

貨號：

KT012103

產(chǎn)品規(guī)格：

100ul

Applications：

IHC/IF

Species：

M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	BRCA2 rabbit polyclonal antibody
Protein full name	Breast cancer type 2 susceptibility protein
Synonyms	Brca2, BRCA2, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCD, FANCD1, GLM3, PNCA2, XRCC11, Breast cancer 2, DNA repair associated, breast cancer 2, Early onset, BRCA2 DNA repair associated
Immunogen	Recombinant protein corresponding to Mouse BRCA2
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm, Nucleus
Uniprot ID	P97929, O35923

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Mouse, Rat	1:1500-1:3000	brain, hippocampus

Background

BRCA2, also named as FACD and FANCD1, is involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. May participate in S phase checkpoint activation.

Images

	Immunohistochemistry of paraffin embedded mouse hippocampus using BRCA2 (GB111138) at dilution of 1:2200 (400x lens)
	Immunohistochemistry of paraffin embedded rat hippocampus using BRCA2 (GB111138) at dilution of 1:1100 (400x lens)
	Immunofluorescence of paraffin embedded mouse brain using BRCA2 (GB111138) at dilution of 1:2200 (400x lens)
	Immunofluorescence of paraffin embedded rat brain using BRCA2 (GB111138) at dilution of 1:2200 (400x lens)
	Immunofluorescence of paraffin embedded rat hippocampus using BRCA2 (GB111138) at dilution of 1:2200 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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