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Product Information
Description |
TLR1 rabbit polyclonal |
Protein full name |
Toll-like receptor 1 |
Synonyms |
Tlr1, TLR1, CD281, TIL, TIL. LPRS5, Rsc786, Toll like receptor 1 |
Immunogen |
Recombinant protein corresponding to Mouse TLR1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cell membrane, Cytoplasm |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
IHC |
Rat |
1: 1000-1: 1500 |
spleen, kidney |
IF |
Rat |
1: 500-1: 2000 |
spleen, kidney |
Background
TLR1 is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The gene encoding TLR1 is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.
Images
Immunohistochemistry analysis of paraffin-embedded rat spleen using TLR1 (GB11886) at dilution of 1: 1000
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Immunohistochemistry analysis of paraffin-embedded rat kidney using TLR1 (GB11886) at dilution of 1: 1000
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Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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