Anti -Tollip Rabbit pAb

價格：在線咨詢

貨號：

DRF101734

產品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	Tollip rabbit polyclonal
Protein full name	Toll-interacting protein
Synonyms	TOLLIP, IL-1RAcPIP, toll interacting protein
Immunogen	Recombinant protein corresponding to Mouse Tollip
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm
Predicted MW.	30 kDa
Observed MW.	30 kDa
Uniprot ID	Q9H0E2, Q9QZ06

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1 :500-1: 1000	brain, spleen, thymus
IHC	Human, Mouse, Rat	1: 1000-1: 2000	liver cancer, spleen, brain, kidney, lung
IF	Human, Mouse, Rat	1: 500-1: 1000	liver cancer, spleen, brain, kidney, lung

Background

The Tollip is the component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates

Images

	Western blot analysis of NCR1 (GB111102) at dilution of 1: 1000 Lane 1: Mouse brain tissue lysate Lane 2: Mouse spleen tissue lysate Lane 3: Mouse thymus tissue lysate Lane 4: Mouse brain tissue lysate Lane 5: Mouse spleen tissue lysate Lane 6: Mouse thymus tissue lysate
	Immunohistochemistry analysis of paraffin-embedded human liver cancer using Tollip (GB111093) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded mouse spleen using Tollip (GB111093) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded rat kidney using Tollip (GB111093) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded rat brain using Tollip (GB111093) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded rat lung using Tollip (GB111093) at dilution of 1: 2000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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