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Product Information
Description | MyD88 rabbit polyclonal |
Protein full name | Myeloid differentiation primary response protein MyD88 |
Synonyms | MYD88, MYD88D, mutant myeloid differentiation primary response 88, myeloid differentiation primary response gene (88) |
Immunogen | KLH conjugated Synthetic peptide corresponding to Human MyD88 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | Nucleus, Cytoplasm |
Uniprot ID | Q99836, P22366, Q6Y1S1 |
Applications
Applications | Species | Dilution | Positive Tissue |
IHC | Human, Mouse, Rat | 1: 1200-1: 2400 | small intestine, lung, pneumonia |
Background
MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS, which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis.
Images
Immunohistochemistry analysis of paraffin-embedded human small intestine using MyD88 (GB111554) at dilution of 1: 1200 |
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Immunohistochemistry analysis of paraffin-embedded mouse lung using MyD88 at dilution of 1: 1200 |
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Immunohistochemistry analysis of paraffin-embedded rat pneumonia using MyD88 at dilution of 1: 1200 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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