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Product Information
Description | FGL2/Prothrombinase rabbit polyclonal |
Protein full name | Fibroleukin |
Synonyms | Cytotoxic T-lymphocyte-specific protein, Fibrinogen-like protein 2, Prothrombinase, Fgl2, Fiblp, pT49, T49, fibrinogen like 2 |
Immunogen | Recombinant protein corresponding to Mouse FGL2/Prothrombinase |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 49 kDa |
Observed MW. | 64 kDa |
Uniprot ID | Q14314 |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human | 1: 500-1: 1000 | Raji, HepG2, SW480 |
Background
FGL2 (fibrinogen like protein 2) is a 70 kDa glycoprotein that belongs to the fibrinogen-related superfamily of proteins which are involved in coagulation, cell adhesion, and transendothelial migration. FGL2 is an important immune regulator of both innate and adaptive response. It is present on the surface of macrophages and endothelial cells, and can be constitutively secreted by CD4+ CD8+ T cell. FGL2 forms a tetrameric complex which is stabilized by interchain disulfide bonds and it exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. The protein may play a role in physiologic functions at mucosal sites.
Images
Western blot analysis of FGL2 (GB111587) at dilution of 1: 1000 Lane 1: Raji cell lysate Lane 2: HepG2 cell lysate Lane 3: SW480 cell lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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