Anti -MCK10/NEP Rabbit pAb

價(jià)格：在線咨詢

貨號：

KT012002

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	MCK10 rabbit polyclonal antibody
Protein full name	Epithelial discoidin domain-containing receptor 1
Synonyms	Cell adhesion kinase, Discoidin receptor tyrosine kinase, HGK2, CAK, EDDR1, NEP, NTRK4, PTK3A, MCK-10, CD167a, DDR1, RTK6, TRKE
Immunogen	KLH conjugated Synthetic peptide corresponding to Human MCK10
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane, Secreted
Uniprot ID	Q08345

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Human	1:400-1:1000	colon, colon cancer, esophagus, ovarian cancer

Background

This protein belongs to a subfamily of tyrosine kinase receptors. The Tyrosine kinase functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases.

Images

	Immunohistochemistry of paraffin embedded human colon using DDR1 (GB111290) at dilution of 1:450 (400x lens)
	Immunohistochemistry of paraffin embedded human colon cancer using DDR1 (GB111290) at dilution of 1:450 (400x lens)
	Immunofluorescence of paraffin embedded human colon cancer using DDR1 (GB111290) at dilution of 1:400 (400x lens)
	Immunofluorescence of paraffin embedded human esophagus using DDR1 (GB111290) at dilution of 1:400 (400x lens)
	Immunofluorescence of paraffin embedded human ovarian cancer using DDR1 (GB111290) at dilution of 1:400 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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