黄色三级视频在线观看|亚洲国产麻豆免费观看|九九精品免视频国产成人|99久久国内精品成人免费|2020久久国产精品性爱|秋霞影院无码尤物在线观看|久久精品人人做人人看最新章|成人国产一区二区三区精品不卡

歡迎,來(lái)到萬(wàn)物生物官方網(wǎng)站!
郵箱:355185756@qq.com
全國(guó)服務(wù)熱線: 400-1016-218
聯(lián)系方式
  • 手機(jī):400-1016-218
  • Q Q:355185756
  • 郵箱:355185756@qq.com
  • 地址:安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室

Anti -MRP1 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011987
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
R/R
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

MRP1 rabbit polyclonal

Protein full name

Multidrug resistance-associated protein 1

Synonyms

ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter, Abcc1, Mrp1, LTC4 transporter

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse MRP1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane

Uniprot ID

Q8CG09




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Rat

1: 800-1: 1600

lymphoid, brain

IF

Rat

1: 400-1: 800

lymphoid, brain




Background


MRP1 is a member of the MRP subfamily of ATPbindingcassette (ABC) transporters . MRP1 protein functions as an organic anion transporter. It has a broad range of substrates, including antineoplastic or therapeutic agent sand the glutathione (GSH) conjugates of these compounds. MRP1 also transports physiological substrates such as folates, GSH and GSH disulfide (GSSG) conjugates of steroids,leukotrienes and prostaglandins. Although MRP1 is generally expressed in normaltissue, upregulation of MRP1 has been found in avariety of solid tumors, including small cell lung cancer, breast cancer, and prostate cancer . Research studies show that over expression of MRP1 facilitates the elimination of therapeutic agents from cancer cells and confers drug resistance in those patients. Research studies also show that elevated expression of MRP1 is a negative prognostic marker for breast cancer and small cell lung cancer, as the level of MRP1 is predictive of the response and toxicity of chemotherapeutic agents in those patients.




Images


image.png

Immunohistochemistry analysis of paraffin-embedded rat lymphoid usingMRP1 (GB111041) at dilution of 1: 1600

image.png

Immunohistochemistry analysis of paraffin-embedded rat brain using MRP1 (GB111041) at dilution of 1: 1600




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


凡合肥萬(wàn)物生物科技有限公司銷售的產(chǎn)品均有嚴(yán)格的質(zhì)量保證。如發(fā)現(xiàn)產(chǎn)品存在包裝規(guī)格疑問(wèn),請(qǐng)于收貨之日起七日內(nèi)向我公司總部或當(dāng)?shù)剞k事處提出,并請(qǐng)保證該產(chǎn)品,以備本公司進(jìn)行核對(duì)檢驗(yàn)。如果發(fā)現(xiàn)有質(zhì)量問(wèn)題,請(qǐng)于收貨后一月內(nèi)保留產(chǎn)品50%以上的量,以便本公司回收產(chǎn)品進(jìn)行質(zhì)檢,確認(rèn)產(chǎn)品質(zhì)量。如逾期,則視為已經(jīng)對(duì)本公司產(chǎn)品進(jìn)行驗(yàn)收。 聲明:如發(fā)生產(chǎn)品索賠事宜,本公司僅在產(chǎn)品價(jià)格范圍內(nèi)酌情賠償,恕不接受超出產(chǎn)品價(jià)格范圍之賠償??蛻粼谑褂眠^(guò)程中有任何技術(shù)問(wèn)題可以撥打技術(shù)售后服務(wù)電話我們隨時(shí)給予解答。

合肥萬(wàn)物生物科技有限公司

客服熱線:400-1016-218

QQ:355185756

地址:安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室

服務(wù)熱線

400-1016-218

功能和特性

價(jià)格和優(yōu)惠

獲取新資料

售后服務(wù)

咨詢微信

價(jià)格咨詢
* 咨詢產(chǎn)品:
* 您的稱呼:
* 聯(lián)系方式:
* 地區(qū)城市:
* 圖片驗(yàn)證:
立即詢價(jià)