Anti -Mesothelin Rabbit pAb

價格：在線咨詢

貨號：

KT011925

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	Mesothelin rabbit polyclonal antibody
Protein full name	Mesothelin
Synonyms	Pre-pro-megakaryocyte-potentiating factor, Megakaryocyte-potentiating factor, MPF, Msln, Mes, CAK1, SMR, SMRP, MAN
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Mesothelin
Isotype	IgG
Purity	Affinity purification
Predicted MW.	69 kDa
Observed MW.	49 kDa
Uniprot ID	Q61468, Q9ERA7

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 500-1: 1000	thymus, heart, lung, testis

Background

Mesothelin is a glycosyl-phosphatidylinositol-anchored glycoprotein present on the cell surface of various human solid tumors. It is expressed on pleural and peritoneal mesothelial cells, but not in other non-neoplastic tissues. The mesothelin gene encodes a 69-71kDa precursor protein that is processed to a 40kDa membrane-bound protein termed mesothelin and a 31kDa shed fragment called megakaryocyte-potentiating factor (MPF) that is released from the cell. Mesothelin is a tumor differentiation antigen present at low levels on a restricted set of normal adult tissues (e.g. mesothelium), and is expressed at high levels in mesotheliomas, as well as ovarian, pancreatic, and lung cancers. Mesothelin may be a new target for immunotherapy.

Images

Western blot analysis of mesothelin（CA125) (GB111016) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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