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Anti -CTLA4 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101626
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

CTLA4 rabbit polyclonal

Protein full name

Cytotoxic T-lymphocyte protein 4

Synonyms

Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CTLA4, ALPS5, CELIAC3, GRD4, GSE, ICOS, IDDM12

Immunogen

KLH conjugated Synthetic peptide

corresponding to Human CTLA4

Isotype

IgG

Purity

Affinity purification

Predicted MW.

25 kDa

Observed MW.

25 kDa

Uniprot ID

P09793




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

spleen, lung




Background


CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.




Images


圖片 1.png

Western blot analysis of CTLA4 (GB111877)

at dilution of 1: 1000

Lane 1: Mouse spleen tissue lysate

Lane 2: Mouse lung tissue lysate

Lane 3: Rat spleen tissue lysate

Lane 4: Rat lung tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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