Anti -Fas Ligand Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

DRF101623

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	Fas Ligand rabbit polyclonal
Protein full name	Tumor necrosis factor ligand superfamily member 6
Synonyms	ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse FASL
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane
Uniprot ID	P25445, P25446, Q63199

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Human, Mouse, Rat	1: 500-1: 3000	Appendix, spleen, Thymus, liver
IF	Mouse, Rat	1: 1500- 1: 3000	small intestine, thymus, lung

Background

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

Images

	Immunohistochemistry analysis of paraffin-embedded human appendix using FasL (GB11090-1) at dilution of 1:1000
	Immunohistochemistry analysis of paraffin-embedded mouse Immunized spleen using FasL (GB11090-1) at dilution of 1:1000
	Immunohistochemistry analysis of paraffin-embedded mouse Immunized thymus using FasL (GB11090-1) at dilution of 1:1000
	Immunohistochemistry analysis of paraffin-embedded rat liver using FasL (GB11090-1) at dilution of 1:1000
	Immunohistochemistry analysis of paraffin-embedded rat spleen using FasL (GB11090-1) at dilution of 1:1000
	Immunofluorescent analysis of paraformaldehyde-fixed mouse small intestine using FasL(GB11090-1) at dilution of 1: 1500
	Immunofluorescent analysis of paraformaldehyde-fixed rat thymus using FasL(GB11090-1) at dilution of 1: 1500
	Immunofluorescent analysis of paraformaldehyde-fixed rat lung using FasL(GB11090-1) at dilution of 1: 3000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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