服務(wù)熱線
400-1016-218
全國(guó)統(tǒng)一服務(wù)熱線
400-1016-218
科研好幫手 專(zhuān)業(yè)生產(chǎn)商
本公司產(chǎn)品僅供科研使用
您現(xiàn)在所在位置:主頁(yè) > 產(chǎn)品中心 > 抗體 >>一抗 >>小G蛋白相關(guān) >> Anti -RAB27A Rabbit pAb
Product Information
Description |
RAB27A rabbit polyclonal antibody |
Protein full name |
Ras-related protein Rab-27A |
Synonyms |
Rab27a, Rab27, Ras-related protein Rab-27A, Ras-related protein Rab27A |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse RAB27A |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
25 kDa |
Observed MW. |
28 kDa |
Uniprot ID |
Q9ERI2, P23640 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 500-1: 1000 |
liver, ovary, kidney |
Background
Rab27a is a member of a large family of Ras-related small GTPases. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Recent studies suggest that Rab27a is associated with melanosomes in pigmented cells and regulates melanosome transport via its interaction with actin-based cellular motors such as myosin Va and myosin VIIa. RAB27A is also required for regulated secretion in cytotoxic T lymphocytes. Rab27a is implicated in several diseases, including Griscelli syndrome, choroideremia, and the Hermansky-Pudlak syndrome mouse model, gunmetal.
Images
|
Western blot analysis of RAB27A at dilution of 1: 500 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
合肥萬(wàn)物生物科技有限公司
客服熱線:400-1016-218
QQ:355185756
地址:安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室