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Anti -CAMK2B Rabbit pAb

價格: 在線咨詢
貨號:
KT012253
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
H/M/R
購買數(shù)量:
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Product Information


Description

CAMK2B rabbit polyclonal antibody

Protein full name

Calcium/calmodulin-dependent protein kinase type II subunit beta

Synonyms

CaM kinase II subunit beta, CaMK-II subunit beta, Camk2b, Camk2d

Immunogen

Recombinant protein corresponding to Mouse CAMK2B

Isotype

IgG

Purity

Affinity purification

Predicted MW.

60 kDa

Observed MW.

60 kDa

Uniprot ID

Q13554, P28652, P08413





Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 300-1: 600

HeLa, SH-SY5Y, U-251MG, Neuro2A, PC-12




Background


CaMKII beta (Calcium/calmodulin-dependent protein kinase type II subunit beta ), also named as CAMK2B, CAM2 or CAMKB, belongs to the protein kinase super family, CAMK Ser/Thr protein kinase family and CaMK subfamily. It is a member of the NMDAR signaling complex in excitatory synapses, it may functions autonomously after Ca2+ calmodulin binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner.




Images


Picture 1.png

Western blot analysis of Camk2b  at dilution of 1: 300




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.
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