Anti -Frizzled 6 Rabbit pAb

價格：在線咨詢

貨號：

KT012214

產品規(guī)格：

100 μL

Applications：

Species：

M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	Frizzled 6 rabbit polyclonal antibody
Protein full name	Frizzled-6
Synonyms	Fz-6, mFz6, Fzd6, NDNC10, Frizzled homolog 6, Frizzled family receptor 6, Frizzled 6 seven transmembrane spanning receptor, hFz6
Immunogen	Recombinant protein corresponding to Mouse Frizzled 6
Isotype	IgG
Purity	Affinity purification
Predicted MW.	79 kDa
Observed MW.	72 kDa
Uniprot ID	Q61089

Applications

Applications	Species	Dilution	Positive Sample
WB	Mouse, Rat	1: 1000-1: 2000	liver, kidney, prostate, pancreas

Background

This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis.

Images

Western blot analysis of Frizzled-6 (GB112220) at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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