Anti -IKB alpha Rabbit pAb

價格：在線咨詢

貨號：

KT012213

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

H,M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	IKB alpha rabbit polyclonal antibody
Protein full name	NF-kappa-B inhibitor alpha
Synonyms	NFKBIA, IKBA, MAD-3, NFKBI, NFKB inhibitor
Immunogen	KLH conjugated Synthetic peptide corresponding to Human IKBα
Isotype	IgG
Purity	Affinity purification
Predicted MW.	36 kDa
Observed MW.	36 kDa
Uniprot ID	P25963, Q9Z1E3

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 500-1: 1000	heart, liver, kidney

Background

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Images

Western blot analysis of IKBα (GB111509) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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