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Anti -XIAP Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT012195
產(chǎn)品規(guī)格:
100ul
Applications:
WB
Species:
H/M
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

XIAP rabbit polyclonal antibody

Protein full name

E3 ubiquitin-protein ligase XIAP

Synonyms

Baculoviral IAP repeat-containing protein 4, IAP-like protein, API3, BIRC4, IAP3, XIAP,

ILP, hILP, Inhibitor of apoptosis protein 3, IAP-3, hIAP3, X-linked IAP

Immunogen

Recombinant protein corresponding to Mouse XIAP

Isotype

IgG

Purity

Affinity purification

Predicted MW.

57 kDa

Observed MW.

57 kDa

Uniprot ID

P98170, Q60989




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse

1: 500-1: 1000

MCF-7, HT-29, Jurkat, Raji, PC-12, HepG2




Background


XIAP, also named as API3, BIRC4 and IAP3, belongs to the IAP family. It has E3 ubiquitin-protein ligase activity. It mediates the proteasomal degradation of target proteins, such as caspase-3, SMAC or AIFM1. XIAP is an inhibitor of caspase-3, -7 and -9. It mediates activation of MAP3K7/TAK1, leading to the activation of NF-kappa-B. XIAP is an apoptotic suppressor. It is ubiquitinated and degraded by the proteasome in apoptotic cells.




Images


Picture 1.png

Western blot analysis of XIAP (GB111208) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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