服務熱線
400-1016-218
聯(lián)系方式
- 手機：400-1016-218
- Q Q：355185756
- 郵箱：355185756@qq.com
- 地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學科技園A401室
Anti -ATG3 Rabbit pAb
價格：
在線咨詢
貨號：
KT012161
產(chǎn)品規(guī)格：
100 μL
Applications：
WB
Species：
H,M
購買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項
Product Information
|
Description |
ATG3 rabbit polyclonal antibody |
|
Protein full name |
Ubiquitin-like-conjugating enzyme ATG3 |
|
Synonyms |
Autophagy-related protein 3, Protein PC3-96, APG3-like, hApg3, ATG3, APG3, APG3L |
|
Immunogen |
Recombinant protein corresponding to Human ATG3 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
36 kDa |
|
Observed MW. |
40 kDa |
|
Uniprot ID |
Q9NT62, Q9CPX6 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse |
1: 500-1: 1000 |
THP-2, A20, HeLa, Jurkat |
Background
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy.
Images
|
|
Western blot analysis of ATG3 (GB111131) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
凡合肥萬物生物科技有限公司銷售的產(chǎn)品均有嚴格的質量保證。如發(fā)現(xiàn)產(chǎn)品存在包裝規(guī)格疑問，請于收貨之日起七日內向我公司總部或當?shù)剞k事處提出，并請保證該產(chǎn)品，以備本公司進行核對檢驗。如果發(fā)現(xiàn)有質量問題，請于收貨后一月內保留產(chǎn)品50%以上的量，以便本公司回收產(chǎn)品進行質檢，確認產(chǎn)品質量。如逾期，則視為已經(jīng)對本公司產(chǎn)品進行驗收。 聲明：如發(fā)生產(chǎn)品索賠事宜，本公司僅在產(chǎn)品價格范圍內酌情賠償，恕不接受超出產(chǎn)品價格范圍之賠償。客戶在使用過程中有任何技術問題可以撥打技術售后服務電話我們隨時給予解答。
合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學科技園A401室