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Product Information
Description |
CREB rabbit polyclonal antibody |
Protein full name |
Cyclic AMP-responsive element-binding protein 1 |
Synonyms |
CREB-1, CAMP-responsive element-binding protein 1, CAMP responsive element binding protein 1, Active transcription factor CREB |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CREB |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
37 kDa |
Observed MW. |
43 kDa |
Uniprot ID |
Q01147, P15337 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain, cerebral cortex, cerebellum, spinal cord |
Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Images
|
Western blot analysis of CREB (GB111052) at dilution of 1: 500 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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