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Anti -Cathepsin D Rabbit pAb

價格: 在線咨詢
貨號:
KT012061
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
M/M
購買數(shù)量:
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Product Information


Description

Cathepsin D rabbit polyclonal antibody

Protein full name

Cathepsin D

Synonyms

Ctsd, CatD, CD, CLN10, CPSD, Epididymis secretory sperm binding protein Li 130P, HEL S 130P, Lysosomal aspartyl peptidase

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Cathepsin D

Isotype

IgG

Purity

Affinity purification

Subcellular location

Lysosome, Secreted

Uniprot ID

P07339, P18242




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Mouse

1: 200-1: 400

liver




Background


CTSD(Cathepsin D) is also named as CPSD,belongs to the peptidase A1 family.It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. The prepro-CTSD isoform has a molecular mass of 52 kDa, the pro-CTSD 48 kDa and the mature CTSD 32 kDa. It is a lysosomal acid protease found in neutrophils and monocytes and involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.Defects in CTSD are the cause of neuronal ceroid lipofuscinosis type 10 (CLN10).This antibody is specific to CTSD.




Images


Picture 1.png

Immunofluorescence of paraffin embedded mouse liver using cathepsinD (GB111861) at dilution of 1:200 (260x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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