Anti -IDH1 Rabbit pAb

價格：在線咨詢

貨號：

KT012029

產品規(guī)格：

100ul

Applications：

Species：

H/M/R

品牌：

萬物

購買數量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	IDH1 rabbit polyclonal antibody
Protein full name	Isocitrate dehydrogenase [NADP] cytoplasmic
Synonyms	Cytosolic NADP-isocitrate dehydrogenase, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, IDH1, Idh1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse IDH1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	47 kDa
Observed MW.	47 kDa
Uniprot ID	O75874, O88844, P41562

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	liver, kidney, stomach

Background

The Isocitrate dehydrogenase cytoplasmic enzyme belongs to the isocitrate and isopropylmalate dehydrogenases family. IDHC catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming ketoglutarate and CO2 in a two step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Ca2+ can bind to IDHC as a complex with isocitrate, acting as a competitive inhibitor of Mg2+. The IDHC enzyme is inactivated by phosphorylation at Ser-113 and contains a clasp-like domain wherein both polypeptide chains in the dimer interlock.

Images

Picture 1.png

Western blot analysis of IDH1 (GB111194) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

凡合肥萬物生物科技有限公司銷售的產品均有嚴格的質量保證。如發(fā)現(xiàn)產品存在包裝規(guī)格疑問，請于收貨之日起七日內向我公司總部或當地辦事處提出，并請保證該產品，以備本公司進行核對檢驗。如果發(fā)現(xiàn)有質量問題，請于收貨后一月內保留產品50%以上的量，以便本公司回收產品進行質檢，確認產品質量。如逾期，則視為已經對本公司產品進行驗收。聲明：如發(fā)生產品索賠事宜，本公司僅在產品價格范圍內酌情賠償，恕不接受超出產品價格范圍之賠償。客戶在使用過程中有任何技術問題可以撥打技術售后服務電話我們隨時給予解答。

合肥萬物生物科技有限公司

客服熱線：400-1016-218

QQ：355185756

地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學科技園A401室