Anti -GRK2 Rabbit pAb

價格：在線咨詢

貨號：

KT012012

產(chǎn)品規(guī)格：

Applications：

Species：

H,M

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	GRK2 rabbit polyclonal antibody
Protein full name	Beta-adrenergic receptor kinase 1
Synonyms	Beta-ARK-1, G-protein-coupled receptor kinase 2, Grk2, Adrbk1
Immunogen	Recombinant protein corresponding to Mouse GRK2
Isotype	IgG
Purity	Affinity purification
Predicted MW.	80 kDa
Observed MW.	80 kDa
Uniprot ID	P25098, Q99MK8

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse	1: 500-1: 1000	spleen, lymph nodes

Background

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

Images

Picture 1.png

Western blot analysis of grk2 (GB111115) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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