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Product Information
Description |
c-Fos rabbit polyclonal antibody |
Protein full name |
Proto-oncogene c-Fos |
Synonyms |
FOS, AP-1, C-p55, Fos proto-oncogene, AP-1 transcription factor subunit |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse c-FOS |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Nucleus, Endoplasmic reticulum, Cytoplasm |
Uniprot ID |
P01100, P01101, P12841 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Human, Mouse, Rat |
1: 200-1: 1000 |
brain, breast cancer, colon cancer, heart, kidney, liver, ovary |
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Images
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Immunohistochemistry of paraffin embedded human breast cancer using c-fos (GB11069) at dilution of 1:600 (200x lens) |
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Immunohistochemistry of paraffin embedded human colon cancer using c-fos (GB11069) at dilution of 1:600 (200x lens) |
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Immunohistochemistry of paraffin embedded mouse ovary using c-fos (GB11069) at dilution of 1:600 (200x lens) |
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Immunohistochemistry of paraffin embedded mouse liver using c-fos (GB11069) at dilution of 1:600 (300x lens) |
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Immunohistochemistry of paraffin embedded rat brain using c-fos (GB11069) at dilution of 1:400 (300x lens) |
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Immunohistochemistry of paraffin embedded rat heart using c-fos (GB11069) at dilution of 1:600 (300x lens) |
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Immunohistochemistry of paraffin embedded rat kidney using c-fos (GB11069) at dilution of 1:600 (300x lens) |
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Immunofluorescence of paraffin embedded rat brain using c-fos (GB11069) at dilution of 1:600 (300x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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