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Anti -Asialoglycoprotein Receptor 1/HL-1 Rabbit pAb
價(jià)格：
在線咨詢
貨號(hào)：
KT011927
產(chǎn)品規(guī)格：
100 μL
Applications：
WB
Species：
MR
購(gòu)買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項(xiàng)
Product Information
|
Description |
ASGR1 rabbit polyclonal antibody |
|
Protein full name |
Asialoglycoprotein receptor 1 |
|
Synonyms |
ASGP-R 1, Hepatic lectin 1, HL-1, mHL-1, Asgr1, Asgr |
|
Immunogen |
Recombinant protein corresponding to Mouse ASGR1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
33 kDa |
|
Observed MW. |
42 kDa |
|
Uniprot ID |
P34927, P02706 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
liver |
Background
Asialoglycoprotein receptor (ASGPR), also known as the hepatic galactose/N-acetylglucosamine (GlcNAc) receptor or Ashwell receptor, is a C-type lectin expressed exclusively in hepatic parenchymal cells. ASGPR consists of two subunits, a major subunit (ASGR1, HL-1) and a minor subunit (ASGR2, HL-2), and specifically recognizes terminal β-linked galactose or GlcNAc on circulating glycoproteins or cells. This receptor plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins that contain terminal galactose or GlcNAc residues. ASGPR may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery.
Images
|
|
Western blot analysis of ASGR1 (GB111336) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室