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Product Information
Description |
Inversin rabbit polyclonal antibody |
Protein full name |
Inversin |
Synonyms |
Inversion of embryo turning homolog, Nephrocystin-2, INVS, INV, NPHP2, Inversin |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human Inversin |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cytoplasm, Nucleus |
Predicted MW. |
118 kDa |
Observed MW. |
118 kDa |
Uniprot ID |
Q9Y283 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Human |
1:500-1:1000 |
HEK293, HepG2, A549, K562 |
IHC/IF |
Human |
1:1000-1:3000 |
colon, liver, liver cancer, lung, renal cancer |
Background
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2.
Images
|
Western blot analysis of Inverin (GB111298) at dilution of 1: 500 |
|
Immunohistochemistry of paraffin embedded human colon using INVS (GB111298) at dilution of 1: 1500 (400x lens) |
|
Immunohistochemistry of paraffin embedded human liver using INVS (GB111298) at dilution of 1: 1500 (400x lens) |
|
Immunohistochemistry of paraffin embedded human renal cancer using INVS (GB111298) at dilution of 1: 1500 (400x lens) |
|
Immunofluorescence of paraffin embedded human liver cancer using INVS (GB111298) at dilution of 1: 1500 (400x lens) |
|
Immunofluorescence of paraffin embedded human lung using INVS (GB111298) at dilution of 1: 1500 (400x lens) |
|
Immunofluorescence of paraffin embedded human renal cancer using INVS (GB111298) at dilution of 1: 1500 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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