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Product Information
Description |
GAP43 mouse monoclonal |
Protein full name |
Neuromodulin |
Synonyms |
GAP43, B-50, PP46, growth associated protein 43 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse GAP43 |
Isotype |
IgG2a |
Purity |
Affinity purification |
Subcellular location |
|
Predicted MW. |
43 kDa |
Observed MW. |
43 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 1000-1: 2000 |
brain, cerebral cortex |
IHC |
Mouse, Rat |
1: 1000-1: 2000 |
cerebellum, spinal cord, hippocampus |
Background
GAP43 has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development, during axonal regeneration and is phosphorylated after long-term potentiation(LTP) and after learning (reference needed). This protein is considered a crucial component of the axon andpresynaptic terminal, its null mutation leading to death within days after birth due to axon pathfinding defects.
Images
|
Western blot analysis of GAP43 (GB12095) at dilution of 1: 2000 |
|
Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using GAP43 (GB12095) at dilution of 1: 2000 |
|
Immunohistochemistry analysis of paraffin-embedded rat spinal cord using GAP43 (GB12095) at dilution of 1: 2000 |
|
Immunohistochemistry analysis of paraffin-embedded rat hippocampus using GAP43 (GB12095) at dilution of 1: 2000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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