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Product Information
Description |
SERPING1 rabbit polyclonal |
Protein full name |
Plasma protease C1 inhibitor |
Synonyms |
C1Inh, C1 esterase inhibitor, C1-inhibiting factor, Serpin G1, Serping1, C1nh, HAE2, HAE1, complement component 1 inhibitor |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse SERPING1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Predicted MW. |
56 kDa |
Observed MW. |
100 kDa |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
kidney, heart |
IHC |
Rat |
1: 1000-1: 2000 |
liver |
Background
C1 Inactivator is a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
Images
|
Western blot analysis of SERPING1 at dilution of 1: 1000 Lane 1: HeLa cell lysate Lane 2: HepG2 cell lysate Lane 3: Jurkat cell lysate Lane 4: SKOV3 cell lysate Lane 5: U251 cell lysate Lane 6: Mouse kidney tissue lysate Lane 7: Mouse heart tissue lysate |
Immunohistochemistry analysis of paraffin-embedded rat liver using SERPING1 at dilution of 1: 2000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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