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Anti -Mast Cell Chymase Rabbit pAb

價格: 在線咨詢
貨號:
DRF101924
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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Product Information


Description

Chymase rabbit polyclonal

Protein full name

Chymase

Synonyms

Alpha-chymase, Mast cell chymase 1, Mast cell chymase 5, mMCP-5, Mast cell protease I, Cma1, Mcpt5

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Chymase

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 1000-1: 2000

skin, stomach, uterus

IF

Mouse, Rat

1: 500-1: 1000

skin, stomach, uterus




Background


This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases.




Images


Immunohistochemistry analysis of paraffin-embedded mouse skin using Chymase (GB111085) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded rat skin using Chymase (GB111085) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse stomach using Chymase (GB111085) at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded rat stomach using Chymase (GB111085) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded rat uterus using Chymase (GB111085) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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