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Product Information
Description |
CD8 alpha rabbit polyclonal |
Protein full name |
T-cell surface glycoprotein CD8 alpha chain |
Synonyms |
T-lymphocyte differentiation antigen T8/Leu-2, CD8a, MAL, Leu2, Leu2 T lymphocyte antigen, Ly 35, LYT3, p32, T8 T cell antigen |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human CD8 alpha |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
|
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Human |
1: 1500-1: 3000 |
colon cancer, colon |
Background
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
Images
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Immunohistochemistry analysis of paraffin-embedded human colon cancer using CD8 alpha (GB12068) at dilution of 1: 3000 |
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Immunohistochemistry analysis of paraffin-embedded human colon using CD8 alpha (GB12068) at dilution of 1: 3000 |
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Immunohistochemistry analysis of paraffin-embedded human lung cancer using CD8 alpha (GB12068) at dilution of 1: 3000 |
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Immunohistochemistry analysis of paraffin-embedded human tonsil using CD8 alpha (GB12068) at dilution of 1: 3000 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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