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Anti -IL-6 Rabbit pAb

價格: 在線咨詢
貨號:
DRF101652
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

IL-6 rabbit polyclonal

Protein full name

Interleukin-6

Synonyms

IL6, BSF2, HGF, HSF, IFNB2, IL-6, BSF-2,

CDF, IFN-beta-2, interleukin 6

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse IL-6

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted

Uniprot ID

P20607, P05231




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse,Rat

1: 500-1: 1600

inflammatory

lung, kidney

IF

Mouse,Rat

1: 200-1: 500

inflammatory

lung, kidney




Background


Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.




Images



blob.png

Immunohistochemistry analysis of paraffin-embedded rat kidney using IL-6

(GB11117) at dilution of 1: 800

blob.png

Immunohistochemistry analysis of paraffin-embedded mouse inflammatory lung using IL-6 (GB11117) at dilution of 1: 800




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


Publications:



Title

Journal

Pubmed ID

Application

1

M10, a Myricetin-3-O-b-D-Lactose Sodium Salt, Prevents Ulcerative Colitis Through Inhibiting Necroptosis in Mice.

Frontiers in Pharmacology

33041798

WB

2

GPA Peptide-Induced Nur77 Localization at Mitochondria Inhibits Inflammation and Oxidative Stress through Activating Autophagy in the Intestine.

Oxidative Medicine and Cellular Longevity

32904539

WB

3

Astragalus membranaceus Injection Suppresses Production of Interleukin-6 by Activating Autophagy through the AMPK-mTOR Pathway in Lipopolysaccharide-Stimulated Macrophages.
Abstract

Oxidative Medicine and Cellular Longevity

32724488

WB

4

Silencing CDC25A inhibits the proliferation of liver cancer cells by downregulating IL-6 in vitro and in vivo.

International Journal of Molecular Medicine

31922225

IHC

5

Hic-5 deficiency protects cerulein-induced chronic pancreatitis via down-regulation of the NF-κB (p65)/IL-6 signalling pathway.

Journal of Cellular and Molecular Medicine

31797546

WB

6

Xiaoyao Pills Prevent Lipopolysaccharide-Induced Depression by Inhibiting Inflammation and Protecting Nerves.

Frontiers in Pharmacology

31798446

IHC

7

MicroRNA-451 and Genistein Ameliorate Nonalcoholic Steatohepatitis in Mice.

International Journal of Molecular Sciences

31816816

WB

8

The JAK inhibitor tofacitinib ameliorates immune-mediated liver injury in mice.

Molecular Medicine Reports

31638166

IHC

9

Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases.

Nature Communications

31040273

IF

10

Induction of pathological changes and impaired expression of cytokines in developing female rat spleen after chronic excess fluoride exposure.

Toxicology and Industrial Health

30463494

IHC

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