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Anti -PAX6 Rabbit pAb

價(jià)格: 在線咨詢
貨號:
KT012237
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
M/R
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

PAX6 rabbit polyclonal antibody

Protein full name

Paired box protein Pax-6

Synonyms

Pax6, PAX6, AN, AN2, D11S812E, FVH1, MGDA, WAGR, paired box 6, ASGD5

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse PAX6

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

P63015, P63016




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Mouse, Rat

1: 500-1: 4000

eye




Background



Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.




Images



Picture 1.png Immunohistochemistry of paraffin embedded mouse eye using PAX6 (GB11777) at dilution of 1:2000 (400x lens)
Picture 2.png

Immunohistochemistry of paraffin embedded rat eye using PAX6 (GB11777) at dilution of 1:2000 (400x lens)

Picture 3.png

Immunofluorescence of paraffin embedded mouse eye using PAX6 (GB11777) at dilution of 1:500 (400x lens)




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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