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Anti -ICAM1 Rabbit pAb

價(jià)格: 在線咨詢
貨號:
KT011890
產(chǎn)品規(guī)格:
100 μL
Applications:
WB/IHC/IF
Species:
HM/MR
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

ICAM 1 rabbit polyclonal antibody

Protein full name

Intercellular adhesion molecule 1

Synonyms

ICAM1, BB2, CD54, P3.58, intercellular adhesion molecule 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse ICAM-1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Membrane

Predicted MW.

58 kDa

Observed MW.

58 kDa

Uniprot ID

P05362, Q00238, P13597



Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse

1: 1000-1: 3000

kidney, liver,lung

IHC/IF

Mouse, Rat

1: 500-1: 5000

kidney, liver



Background


ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.(Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins . Acts as a receptor for Coxsackievirus A21 capsid proteins . Upon Kaposis sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell .




Images




Western blot analysis of ICAM1 (GB11106) at dilution of 1: 1000

Immunohistochemistry of paraffin embedded mouse kidney using ICAM1 (GB11106) at dilution of 1: 6000 (200x lens)

Immunohistochemistry of paraffin embedded mouse liver using ICAM1 (GB11106) at dilution of 1: 6000 (200x lens)

Immunohistochemistry of paraffin embedded rat kidney using ICAM1 (GB11106) at dilution of 1: 6000 (200x lens)




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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