服務(wù)熱線
400-1016-218
全國統(tǒng)一服務(wù)熱線
400-1016-218
科研好幫手 專業(yè)生產(chǎn)商
本公司產(chǎn)品僅供科研使用
您現(xiàn)在所在位置:主頁 > 產(chǎn)品中心 > 抗體 >>一抗 >>細(xì)胞連接 >> Anti -ICAM1 Rabbit pAb
Product Information
Description |
ICAM 1 rabbit polyclonal antibody |
Protein full name |
Intercellular adhesion molecule 1 |
Synonyms |
ICAM1, BB2, CD54, P3.58, intercellular adhesion molecule 1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse ICAM-1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Membrane |
Predicted MW. |
58 kDa |
Observed MW. |
58 kDa |
Uniprot ID |
P05362, Q00238, P13597 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Human, Mouse |
1: 1000-1: 3000 |
kidney, liver,lung |
IHC/IF |
Mouse, Rat |
1: 500-1: 5000 |
kidney, liver |
Background
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.(Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins . Acts as a receptor for Coxsackievirus A21 capsid proteins . Upon Kaposis sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell .
Images
|
Western blot analysis of ICAM1 (GB11106) at dilution of 1: 1000 |
|
Immunohistochemistry of paraffin embedded mouse kidney using ICAM1 (GB11106) at dilution of 1: 6000 (200x lens) |
|
Immunohistochemistry of paraffin embedded mouse liver using ICAM1 (GB11106) at dilution of 1: 6000 (200x lens) |
|
Immunohistochemistry of paraffin embedded rat kidney using ICAM1 (GB11106) at dilution of 1: 6000 (200x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.
合肥萬物生物科技有限公司
客服熱線:400-1016-218
QQ:355185756
地址:安徽省合肥市高新區(qū)黃山路602號合肥國家大學(xué)科技園A401室