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Product Information
Description |
TNNC1 rabbit polyclonal antibody |
Protein full name |
Troponin C, slow skeletal and cardiac muscles |
Synonyms |
Tnnc1, TNNC1, CMD1Z, CMH13, TN-C, TNC, TNNC, Troponin C type 1, Troponin C1, Slow skeletal and cardiac type |
Immunogen |
Recombinant protein corresponding to Mouse TNNC1 |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Cytoplasm |
Predicted MW. |
18 kDa |
Observed MW. |
18 kDa |
Uniprot ID |
P19123 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Mouse, Rat |
1: 500-1: 1000 |
heart, lung, skeletal muscle, liver |
IHC/IF |
Mouse, Rat |
1: 800-1: 3000 |
heart, lung, myocardial infarction, Skeletal muscle |
Background
Troponin I (TnI), troponin T (TnT) , troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Images
|
Western blot analysis of Tncc (GB111243) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded mouse myocardial infarction using TnCC (GB111243) at dilution of 1: 800 (400x lens) |
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Immunohistochemistry of paraffin embedded rat heart using TnCC (GB111243) at dilution of 1: 800 (400x lens) |
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Immunofluorescence of paraffin embedded mouse lung using TnCC (GB111243) at dilution of 1: 1600 (400x lens) |
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Immunofluorescence of paraffin embedded mouse skeletal muscle using TnCC (GB111243) at dilution of 1: 1600 (400x lens) |
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Immunofluorescence of paraffin embedded rat heart using TnCC (GB111243) at dilution of 1: 1600 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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