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Product Information
Description |
Cyclin E1 rabbit polyclonal |
Protein full name |
G1/S-specific cyclin-E1 |
Synonyms |
CCNE1, CCNE, pcyclin E1, Cyclin E1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human Cyclin E1 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
47 kDa |
Observed MW. |
47 kDa |
Uniprot ID |
P24864, Q61457, P39949 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 900 |
testis, colon, placenta |
Background
Cyclin E1 (CCNE1) is a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. CCNE1, an essential cyclin activating Cdk2, regulates the G1-S phase transition of the mammalian cell division cycle. Its timing expression plays a direct role in the initiation of DNA replication , the control of histone biosynthesis, and the centrosome cycle. CCNE1 is associated with disease progression in various malignancies and is associated clinically with poor prognosis.
Images
|
Western blot analysis of Cyclin E1
at dilution of 1: 500 Lane 1: HeLa cell lysate Lane 2: MCF7 cell lysate Lane 3: K562 cell lysate Lane 4: Mouse testis tissue lysate Lane 5: Mouse colon tissue lysate Lane 6: Mouse placenta tissue lysate Lane 7: Rat testis tissue lysate Lane 8: Rat colon tissue lysate Lane 9: Rat placenta tissue lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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