Anti -Cyclin E1 Rabbit pAb

價格：在線咨詢

貨號：

KT011864

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

H,M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	Cyclin E1 rabbit polyclonal antibody
Protein full name	G1/S-specific cyclin-E1
Synonyms	CCNE1, CCNE, pcyclin E1, Cyclin E1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Cyclin E1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Nucleus
Uniprot ID	P24864, Q61457

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Human, Mouse, Rat	1: 250-1: 1000	colon, placenta, testis

Background

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.

Images

	Immunohistochemistry of paraffin embedded human placenta using cyclinE1 (GB111937) at dilution of 1:500 (400x lens)
	Immunohistochemistry of paraffin embedded mouse testis using cyclinE1 (GB111937) at dilution of 1:500 (300x lens)
	Immunohistochemistry of paraffin embedded mouse colon using cyclinE1 (GB111937) at dilution of 1:500 (400x lens)
	Immunohistochemistry of paraffin embedded mouse placenta using cyclinE1 (GB111937) at dilution of 1:500 (400x lens)
	Immunohistochemistry of paraffin embedded rat testis using cyclinE1 (GB111937) at dilution of 1:500 (300x lens)
	Immunohistochemistry of paraffin embedded rat placenta using cyclinE1 (GB111937) at dilution of 1:500 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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