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Product Information
Description |
Calbindin mouse monoclonal antibody |
Protein full name |
Calbindin |
Synonyms |
Calbindin D28, D-28K, PCD-29, Spot 35 protein, Calb1, CAB27,Vitamin D dependent calcium binding protein |
Immunogen |
Recombinant protein corresponding to Mouse Calbindin |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Nucleus, Cytoplasm |
Predicted MW. |
30 kDa |
Observed MW. |
30 kDa |
Uniprot ID |
P05937, P12658, P07171 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain, cerebral cortex, kidney |
IHC/IF |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, kidney, renal cancer |
Background
Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kD protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The neurons in brains of patients with Huntington disease are calbindin-depleted.
Images
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Western blot analysis of CALB1 (GB12268) at dilution of 1: 1000 |
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Immunohistochemistry of paraffin embedded human kidney using calb1 (GB12268) at dilution of 1: 500 ( lens)
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Immunohistochemistry of paraffin embedded human renal cancer using calb1 (GB12268) at dilution of 1: 500 ( lens)
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Immunohistochemistry of paraffin embedded mouse brain using calb1 (GB12268) at dilution of 1: 500 ( lens)
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Immunohistochemistry of paraffin embedded mouse kidney using calb1 (GB12268) at dilution of 1: 500 ( lens)
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Immunohistochemistry of paraffin embedded rat brain using calb1 (GB12268) at dilution of 1: 500 ( lens)
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Immunohistochemistry of paraffin embedded rat kidney using calb1 (GB12268) at dilution of 1: 500 ( lens)
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Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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