服務(wù)熱線
400-1016-218
聯(lián)系方式
- 手機：400-1016-218
- Q Q：355185756
- 郵箱：355185756@qq.com
- 地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學(xué)科技園A401室
ti -Tyrosine Hydroxylase Mouse mAb
價格：
在線咨詢
貨號：
KT011753
產(chǎn)品規(guī)格：
100 μL
Applications：
IHC/IF
Species：
M/R
購買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項
Product Information
|
Description |
Tyrosine Hydroxylase mouse monoclonal antibody |
|
Protein full name |
Tyrosine 3-monooxygenase |
|
Synonyms |
TH, Th, DYT14, DYT5b, TYH, tyrosine hydroxylase, Tyrosine hydroxylase |
|
Immunogen |
Recombinant protein corresponding to Mouse Tyrosine Hydroxylase |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm, Axon |
|
Uniprot ID |
P24529,P04177 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Mouse, Rat |
1: 500-1: 3000 |
brain, corpus striatum, substantia nigra |
Background
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA). It does so using molecular oxygen(O2), as well as iron (Fe2+) and tetrahydrobiopterin as cofactors. L-DOPA is a precursor for dopamine, which, in turn, is a precursor for the important neurotransmitters norepinephrine (noradrenaline) and epinephrine(adrenaline). Tyrosine hydroxylase catalyzes the rate limiting step in this synthesis of catecholamines. In humans, tyrosine hydroxylase is encoded by the TH gene,and the enzyme is present in the central nervous system (CNS), peripheral sympathetic neurons and the adrenal medulla.Tyrosine hydroxylase, phenylalanine hydroxylase and tryptophan hydroxylase together make up the family of aromatic amino acid hydroxylases(AAAHs).
Images
|
|
Immunohistochemistry of paraffin embedded mouse brain using TH (GB12181) at dilution of 1: 1500 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat brain using TH (GB12181) at dilution of 1: 1500 (400x lens) |
|
Immunofluorescence of paraffin embedded mouse corpus striatum using TH (GB12181) at dilution of 1: 500 (400x lens) |
|
|
Immunofluorescence of paraffin embedded mouse substantia nigra using TH (GB12181) at dilution of 1: 500 (400x lens) |
|
|
Immunofluorescence of paraffin embedded rat substantia nigra using TH (GB12181) at dilution of 1: 500 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
凡合肥萬物生物科技有限公司銷售的產(chǎn)品均有嚴格的質(zhì)量保證。如發(fā)現(xiàn)產(chǎn)品存在包裝規(guī)格疑問，請于收貨之日起七日內(nèi)向我公司總部或當?shù)剞k事處提出，并請保證該產(chǎn)品，以備本公司進行核對檢驗。如果發(fā)現(xiàn)有質(zhì)量問題，請于收貨后一月內(nèi)保留產(chǎn)品50%以上的量，以便本公司回收產(chǎn)品進行質(zhì)檢，確認產(chǎn)品質(zhì)量。如逾期，則視為已經(jīng)對本公司產(chǎn)品進行驗收。 聲明：如發(fā)生產(chǎn)品索賠事宜，本公司僅在產(chǎn)品價格范圍內(nèi)酌情賠償，恕不接受超出產(chǎn)品價格范圍之賠償?？蛻粼谑褂眠^程中有任何技術(shù)問題可以撥打技術(shù)售后服務(wù)電話我們隨時給予解答。
合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學(xué)科技園A401室