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Product Information
Description |
PGP9.5 mouse monoclonal antibody |
Protein full name |
Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
Synonyms |
UCH-L1, Neuron cytoplasmic protein 9.5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1, Uchl1 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse PGP9.5 |
Isotype |
IgG1 |
Purity |
Affinity purification |
Subcellular location |
Cytoplasm, Endoplasmic reticulum, Membrane |
Predicted MW. |
27 kDa |
Observed MW. |
27 kDa |
Uniprot ID |
P09936, Q9R0P9, Q00981 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
WB |
Human, Mouse, Rat |
1: 1000-1: 2000 |
cerebral cortex, hippocampus, brain |
IHC/IF |
Human, Mouse, Rat |
1: 1000-1: 2000 |
brain, colon, esophagus cancer, stomach |
Background
UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons. This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm . And UCHL1 is a Parkinson's disease susceptibility gene.
Images
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Western blot analysis of PGP9.5 (GB12159) at dilution of 1: 1000 |
Immunohistochemistry of paraffin embedded human esophagus cancer using PGP9.5 (GB12159) at dilution of 1: 1000 (400x lens) | |
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Immunohistochemistry of paraffin embedded human stomach using PGP9.5 (GB12159) at dilution of 1: 1000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse brain using PGP9.5 (GB12159) at dilution of 1: 1000 (400x lens) |
|
Immunohistochemistry of paraffin embedded mouse colon using PGP9.5 (GB12159) at dilution of 1: 1000 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat brain using PGP9.5 (GB12159) at dilution of 1: 1000 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat colon using PGP9.5 (GB12159) at dilution of 1: 1000 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat stomach using PGP9.5 (GB12159) at dilution of 1: 1000 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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