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Product Information
Description |
Myelin Protein Zero rabbit polyclonal antibody |
Protein full name |
Myelin protein P0 |
Synonyms |
Mpz, Myelin protein P0, CHM, CMT1, CMT1B, CMT2I, CMT2J, CMT4E, CMTDI3, CMTDID, DSS, HMSNIB, MPP, P0, Myelin protein zero, CHN2 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Myelin Protein Zero |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
28 kDa |
Observed MW. |
28 kDa |
Uniprot ID |
P27573, P06907 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Mouse, Rat |
1: 500-1: 1000 |
optic nerve, spinal cord |
Background
Myelin protein zero (P0, MPZ) is a single membrane glycoprotein encoded by the MPZ gene. P0 is a major structural component of the myelin sheath in the peripheral nervous system (PNS). Myelin protein zero is expressed by Schwann cells and accounts for over 50% of all proteins in the peripheral nervous system, making it the most common protein expressed in the PNS. Mutations in myelin protein zero can cause myelin deficiency and are associated with neuropathies like Charcot–Marie–Tooth disease and Dejerine–Sottas disease.
Images
Western blot analysis of Myelin Protein Zero (GB11747) at dilution of 1: 1000 Lane 1: Mouse optic nerve tissue lysate Lane 2: Mouse spinal cord tissue lysate Lane 3: Mouse hypophysis tissue lysate Lane 4: Rat optic nerve tissue lysate Lane 5: Rat spinal cord tissue lysate |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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