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Product Information
Description |
CCR6 rabbit polyclonal |
Protein full name |
C-C chemokine receptor type 6 |
Synonyms |
CCR6, BN-1, C-C CKR-6, CC-CKR-6, CCR-6, CD196, CKR-L3, CKRL3, CMKBR6, DCR2, DRY6, GPR29, GPRCY4, STRL22, C-C motif chemokine receptor 6 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human CCR6 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
42 kDa |
Observed MW. |
42 kDa |
Uniprot ID |
Applications
applications |
species |
dilution |
positive tissue |
WB |
Human, Mouse, Rat |
1: 1000-1: 2000 |
lymph gland, thymus, splenitis |
Background
Chemokine receptor 6 also known as CCR6 is a CC chemokine receptor protein which in humans is encoded by the CCR6 gene. CCR6 has also recently been designated CD196 (cluster of differentiation 196). This protein belongs to family A of G protein-coupled receptor superfamily. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dendritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
Images
Western blot analysis of CCR6 (GB11585) at dilution of 1: 1000 Lane 1: MCF7 cell lysate Lane 2: HepG2 cell lysate Lane 3: L02 cell lysate Lane 4: Mouse lymph gland tissue lysate Lane 5: Mouse thymus tissue lysate Lane 6: Mouse splenitis tissue lysate Lane 7: Rat lymph gland tissue lysate Lane 8: Rat thymus tissue lysate Lane 9: Rat splenitis tissue lysate
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Storage
Storage |
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles |
Storage Buffer |
PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.
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