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Product Information
Description |
IL-17A Receptor rabbit polyclonal |
Protein full name |
Interleukin-17 receptor A |
Synonyms |
IL17RA, CANDF5, CD217, CDw217, IL-17RA, IL17R, hIL-17R, interleukin 17 receptor A, IMD51, IL-17A Receptor |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human IL-17A Receptor |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
96 kDa |
Observed MW. |
110 kDa |
Uniprot ID |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human |
1: 500-1: 1000 |
Jurkat, HTP-1, A20 |
Background
Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.
Images
Western blot analysis of IL-17A Receptor (GB11586) at dilution of 1: 600 Lane 1: Jurkat cell lysate Lane 2: HTP-1 cell lysate Lane 3: A20 cell lysate
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Storage
Storage |
Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles |
Storage Buffer |
PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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