Anti -MCM2 Rabbit pAb

價格：在線咨詢

貨號：

DRF101287

產(chǎn)品規(guī)格：

100 μL

Applications：

WB | IHC | IF

Species：

H,M,R | H,M,R | H,M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	MCM2 rabbit polyclonal
Protein full name	DNA replication licensing factor MCM2
Synonyms	Minichromosome maintenance protein 2 homolog, Nuclear protein BM28, Mcm2, Bm28, Cdcl1, Kiaa0030, Mcmd2
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse MCM2
Isotype	IgG
Purity	Affinity purification
Subcellular location	Nucleus
Predicted MW.	102 kDa
Observed MW.	130 kDa
Uniprot ID	P49736, P97310, D3ZP96

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	thymus
IHC	Human, Mouse, Rat	1: 1000-1: 4000	lung cancer, brain, colon cancer, thymus, lung
IF	Human, Mouse, Rat	1: 1000-1: 3000	brain, lung, thymus

Background

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.

Images

	Western blot analysis of MCM2 (GB111162) at dilution of 1: 1000 Lane 1: Hela cell lysate Lane 2: Jurkat cell lysate Lane 3: MCF7 cell lysate Lane 4: SW480 cell lysate Lane 5: Raji cell lysate Lane 6: Mouse thymus tissue lysate Lane 7: Rat thymus tissue lysate
	Immunohistochemistry analysis of paraffin-embedded human lung cancer using MCM2 (GB111162) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded human colon cancer using MCM2 (GB111162) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded mouse brain using MCM2 (GB111162) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded mouse thymus using MCM2 (GB111162) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded rat thymus using MCM2 (GB111162) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded rat lung using MCM2 (GB111162) at dilution of 1: 2000
	Immunofluorescent analysis of paraffin-embedded mouse brain using MCM2 (GB111162) at dilution of 1: 2000
	Immunofluorescent analysis of paraffin-embedded mouse lung using MCM2 (GB111162) at dilution of 1: 2000
	Immunofluorescent analysis of paraffin-embedded rat thymus using MCM2 (GB111162) at dilution of 1: 2000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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